Transcriptional output, cell-type densities, and normalization in spatial transcriptomics

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cell type-specific transcriptomics in the brain.

Editor's Note: Toolboxes are intended to describe and evaluate methods that are becoming widely relevant to the neuroscience community or to provide a critical analysis of established techniques. For more information, see http://www.jneurosci.org/misc/ ifa_minireviews.dtl. Sequencing of multiple mammalian ge-nomes, together with the development of whole-transcriptome profiling technologies , ha...

متن کامل

Spatial Normalization

We describe a comprehensive framework for performing rapid and automatic non-label based nonlinear spatial normalizations. The approach adopted minimizes the residual squared diierence between an image and a template of the same modality. In order to reduce the number of parameters to be tted, the nonlinear warps are described by a linear combination of low spatial frequency basis functions. Th...

متن کامل

: metadiscourse in introduction sections of applied linguistics and physics research articles: exploring variation in frequency and type

abstract in written mode of language, metadiscourse markers are used commonly to help writers in general and academic writers in particular to produce coherent and professional texts. the purpose of the present study was to compare introduction sections of applied linguistics and physics articles regarding their use of interactive and interactional metadiscourse markers based on the model pro...

15 صفحه اول

Measuring Information Spatial Densities

A novel definition of the stimulus-specific information is presented, which is particularly useful when the stimuli constitute a continuous and metric set, as, for example, position in space. The approach allows one to build the spatial information distribution of a given neural response. The method is applied to the investigation of putative differences in the coding of position in hippocampus...

متن کامل

Transcriptional regulation of E-cadherin and oncoprotein E7 by valproic acid in HPV positive cell lines

Objective(s): Valproic acid (VPA) has proven to be as one of the most promising useful drug with anticancer properties.In this study, we investigate the VPA effects on E-cadherin expression in HeLa, TC1, MKN45, and HCT116 cell lines.  This study assesses the effects of VPA on human papillomavirus E7 expression in HPV positive cell lines. Materials and Methods: Cell lines were treated by2 mmol/...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Molecular Cell Biology

سال: 2020

ISSN: 1674-2788,1759-4685

DOI: 10.1093/jmcb/mjaa028